Contact prospects again when a connection is accepted or the next message in an outreach sequence is due.
Recap discovery calls with the agreed next step and timing.
Your prospect gets a short sales call follow-up email with the agreed next step and timing, while you get a copy and any open questions.
Send one follow-up in the original thread when a prospect stays silent.
Your sales follow-up emails go out when due if prospects stay quiet, and their replies stand out in your inbox.